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October 05, 2019
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William G. Cioffi, MD, FACS

J. Murray Beardsley Professor and Chairman, Warren Alpert Medical School at Brown University
Department of Surgery Surgeon-in-Chief, Rhode Island Hospital and The Miriam Hospital
President, Brown Surgical Associates

(401) 553-8348

Accepting New Patients

William G. Cioffi, MD, FACS, is the surgeon-in-chief at the Miriam and Rhode Island hospitals. He is also the J. Murray Beardsley Professor and chairman of the department of surgery at The Warren Alpert Medical School of Brown University. Previously he was the chief of the burn study branch at the Institute of Surgical Research at Fort Sam Houston, Texas. He received his medical degree from the University of Vermont College of Medicine and completed his residency in general surgery at the Medical Center Hospital of Vermont.

He serves on various hospital, university and national committees dedicated to improving patient care for critically ill surgical patients. He is the past president of the American Association for the Surgery of Trauma, the International Surgical Group, the Surgical Critical Care Program Directors Society, the Society of University Surgeons and the North American Burn Society.

Dr. Cioffi is currently the treasurer of the American College of Surgeons and the International Society of Burn Injuries and secretary of the American Burn Association. He is on the Executive Committee of the Board of Governors of the American College of Surgeons and serves on multiple other committees for the college and is a member of The Halsted Society, American Surgical Association, Association for Academic Surgery, and Southern Surgical Association. Cioffi has also served on the editorial boards of such journals as Shock, Journal of Trauma, and Surgery and the American Journal of Surgery.

A board-certified general surgeon with added qualifications in surgical critical care, Cioffi’s clinical expertise and research interests are in the areas of pancreatic, oncologic, colorectal and trauma surgery. He has authored or co-authored more than 460 articles, book chapters and abstracts and continues to lecture nationally and internationally in his field.

Specialties

Board Certification: American Board of Surgery (General Surgery, Surgical Critical Care)

Education: The Robert Larner MD College of Medicine at the University of Vermont, Burlington, VT

Residency: General Surgery - University of Vermont Medical Center, Burlington, VT

Fellowship: Surgical Critical Care - Brook Army Medical Center,San Antonio,TX

Memberships in Societies:
Fellow - American College of Surgeons (FACS)
American Association for the Surgery of Trauma
American Burn Association; North American Burn Society
International Society for Burn Injuries
Association for Academic Surgery
American Surgical Association
Coalition for National Trauma Care
Shock Society
Society of Critical Care Medicine
International Association for Surgical Metabolism and Nutrition
International Society of Surgery
International Surgical Group
Surgical Infection Society
Society of University Surgeons
The Halsted Society
John H. David Surgical Society
New England Surgical Society
Rhode Island Medical Society
Providence Surgical Society
Boston Surgical Society
Southern Surgical Association

Hospital Affiliations:
The Miriam Hospital
Rhode Island Hospital

  1. Cioffi WG, Ashikaga T, Gamelli RL: Probability of surviving postoperative acute renal failure: Development of a prognostic index. Ann Surg 200:205-211, 1984.
  2. Cioffi WG, Hebert JC, Gamelli RL, Foster RS: The quantity and function of pulmonary alveolar macrophages after splenectomy and C. parvum. J Trauma 25:405-409, 1985.
  3. Cioffi WG, Gamelli RL, DeMeules JE: The effect of thermal injury on in vitro cardiac function in rats. J Trauma 26:638-642, 1986.
  4. Cioffi WG, DeMeules JE, Wait RB: Renal vascular reactivity in jaundice. Surg 100:356-362, 1986.
  5. Graves TA, Cioffi WG, McManus WF, Mason AD, Pruitt BA: Fluid resuscitation of infants and children with massive thermal injury. J Trauma 28:1656-1659, 1988.
  6. Cioffi WG, DeMeules JE, Gamelli RC: Vascular reactivity in thermal injury. Circ Shock 25:309-317, 1988.
  7. Cioffi WG, Graves TA, McManus WF, Pruitt BA: High-frequency percussive ventilation in patients with inhalation injury. J Trauma 29:350-354, 1989.
  8. Graves TA, Cioffi WG, Mason AD, McManus WF, Pruitt BA: Relationship of transfusion and infection in a burn population. J Trauma 29:948-954, 1989.
  9. Cioffi WG, Pruitt BA: Aeromedical transport of the thermally injured patient. Medical Corps International 4:23-27, 1989.
  10. Luster SH, Patterson PE, Cioffi WG, et al: An evaluation device for quantifying joint stiffness in the burned hand. J of Burn Care & Rehabilitation 11:312-317, 1990.
  11. Pruitt BA, Cioffi WG, Shimazu T, Ikeuchi H, Mason AD: Evaluation and management of patients with inhalation injury. J Trauma 30:S63-S68, 1990.
  12. Cioffi WG, Burleson DG, Jordan BS, Becker WK, McManus WF, Mason AD, Pruitt BA: Effects of granulocyte macrophage colony-stimulating factor on burned patients. Arch Surg 126:74-79, 1991.
  13. Becker WK, Cioffi WG, McManus WF, et al.: Fungal burn wound infection: A 10-year experience. Arch Surg 126:44-48, 1991.
  14. Carlson DE, Cioffi WG, Mason AD, et al: Evaluation of serum visceral protein levels as indicators of nitrogen balance in the thermally injured patient. JPEN 15:440-444, 1991.
  15. Cioffi WG, Rue LW, Graves TA, McManus WF, Mason AD, Pruitt BA: Prophylactic use of high-frequency ventilators in patients with inhalation injury. Ann Surg 213:575-582, 1991.
  16. Cioffi WG, Vaughan GM, Heironimus JD, Jordan BS, Mason AD, Pruitt BA: Dissociation of blood volume and flow in regulation of salt and water balance in burn patients. Ann Surg 214:213-220, 1991.
  17. Cioffi WG, Rue LW: Resuscitation of thermally injured patients. Critical Care Nursing Clinics of North America 3:181-189, 1991.
  18. LeVoyer T, Cioffi WG, Pratt L, Shippee R, McManus WF, Mason AD, Pruitt BA: Alterations in intestinal permeability after thermal injury. Arch Surg 127:26-30, 1992.
  19. Lynch TJ, Possidente CJ, Cioffi WG, Hebert JC: Multidisciplinary protocol for determining aminoglycoside dosage. Am J Hosp Pharm 49:109-115, 1992.
  20. Carlson DE, Cioffi WG, Mason AD, McManus WF, Pruitt BA: Resting energy expenditure in patients with thermal injuries. Surg Gynecol Obstet 174:270-276, 1992.
  21. Shippee RL, Johnson AA, Cioffi WG, Lasko J, LeVoyer TE, Jordan BS: Simultaneous determination of lactulose and mannitol in urine of burn patients by gas-liquid chromatography. Clin Chem 38:343-345, 1992.
  22. Rue LW, Sheridan RL, Cioffi WG, Rush R, McManus WF, Pruitt BA: Thromboembolic complications in thermally injured patients. World J Surg 16:1151-5, 1992.
  23. Cioffi WG, Burleson DG, Jordan BS, Mason AD, Pruitt BA: Granulocyte oxidative activity following thermal injury. Surgery 112:860-5, 1992.
  24. Drost A, Burleson DG, Cioffi WG, Mason AD: Plasma cytokines following thermal injury and their relationship to infection. Ann Surg 218:74-78, 1993.
  25. Graves TA, Cioffi WG, Vaughan GM, Pratt L, Heironimus J D, McManus WF, Pruitt BA: The renal effects of low dose dopamine in thermally injured patients. J Trauma 35:97-102, discussion: 102-103, 1993.
  26. Rue LW III, Cioffi WG, Mason AD, McManus WF, Pruitt BA: Improved survival of burn patients with inhalation injury. Arch Surg 128:772-780, 1993.
  27. Rue LW, Cioffi WG, McManus WF, Pruitt BA: Wound closure and outcome in extensively burned patients treated with cultured autologous keratinocytes. J Trauma 34:662-668, 1993.
  28. Driscoll DM, Cioffi WG, Molter NC, McManus WF, Mason AD, Pruitt BA: Intragastric pH monitoring. J Burn Care Rehab 14:517-524, 1993.
  29. Drost A, Burleson DG, Cioffi WG, Jordan BS, Mason AD, Pruitt BA: Plasma cytokines following thermal injury and their relationship with patient mortality, burn size, and time post-burn. J Trauma 35:335-339, 1993.
  30. Milner EA, Cioffi WG, Mason AD, McManus WF, Pruitt BA: Accuracy of urinary urea nitrogen for predicting total urinary nitrogen in thermally injured patients. JPEN 17:414-416, 1993.
  31. Cioffi WG, deLemos RA, Coalson JJ, Gerstmann DA, Pruitt BA: Decreased pulmonary damage in primates with inhalation injury treated with high-frequency ventilation. Ann Surg 218:328-335, discussion 335-337, 1993.
  32. Cioffi WG, Burleson DG, Pruitt BA: Leukocyte responses to injury. Arch Surg 128:1260-1267, 1993.
  33. Barillo DJ, Cioffi WG, McManus WF, Pruitt BA: Vehicle-related burn injuries. Proceedings of the Association for the Advancement of Automotive Medicine. 37:209-218, 1993.
  34. Milner EA, Cioffi WG, McManus WF, Pruitt BA: Superior mesenteric artery syndrome in a burn patient. Nutr Clin Pract 8:264-266, 1993.
  35. Ogura H, Cioffi WG, Okerberg CV, Johnson AA, Guzman RF, Mason AD, Pruitt BA: The effects of pentoxifylline on pulmonary function following smoke inhalation. J Surg Res 56:242-250, 1994.
  36. Cioffi WG, McManus A, Rue LW III, Mason AD, McManus WF, Pruitt BA: Comparison of acid-neutralizing and non-acid neutralizing stress ulcer prophylaxis in thermally injured patients. J Trauma 36:544-547, 1994.
  37. Ogura H, Cioffi WG, Jordan BS, Okerberg CV, Johnson AA, Mason AD, Pruitt BA: The effect of inhaled nitric oxide on smoke inhalation injury in an ovine model. J Trauma 37:294-302, 1994.
  38. Fitzpatrick JC, Cioffi WG, Cheu HW, Pruitt BA: Predicting ventilation failure in children with inhalation injury. J Pediatric Surg 29:1122-1126, 1994.
  39. Ogura H, Cioffi WG, Offner PJ, Jordan BS, Johnson AA, Pruitt BA: The effect of inhaled nitric oxide on pulmonary function after sepsis in a swine model. Surg 116:313-321, 1994.
  40. Milner EA, Cioffi WG, Mason AD, McManus WF, Pruitt BA: A longitudinal study of resting energy expenditure in thermally injured patients. J Trauma 37:167-170, 1994.
  41. Cioffi WG, Gore DC, Rue LW III, Carrougher G, Guler HP, McManus WF, Pruitt BA: Insulin-like growth factor-1 lowers protein oxidation in patients with thermal injury. Ann Surg 220:310-316, 1994.
  42. Ogura H, Saitoh D, Johnson AA, Mason AD, Pruitt BA, Cioffi WG: The effect of inhaled nitric oxide on pulmonary ventilation-perfusion matching following smoke inhalation injury. J Trauma 37:893-898, 1994.
  43. Ogura H, Offner PJ, Saitoh D, Jordan BS, Johnson AA, Pruitt BA, Cioffi WG: The pulmonary effect of nitric oxide synthase inhibition following sepsis in a swine model. Arch Surg 129:1233-1239, 1994.
  44. Burleson DG, Cioffi WG, Mason AD, Pruitt BA: Antigen expression of lymphoid-cells in burned and toxic epidermal necrolysis (TEN) patients. The FASEB J 8: 752, 1994.
  45. Kelemen JJ, Cioffi WG, McManus WF, Mason AD, Pruitt BA: Burn center care for patients with toxic epidermal necrolysis. J Am Coll Surg 180:273-278, 1995.
  46. Cioffi WG, Ogura H: Inhaled nitric oxide in acute lung disease. New Horizons 3:73-85, 1995.
  47. Mozingo DW, Cioffi WG, McManus WF, Pruitt BA: Peritoneal lavage in the diagnosis of acute surgical abdomen following thermal injury. J Trauma 38:5-7, 1995.
  48. Rue LW III, Cioffi WG, Mason AD, McManus WF, Pruitt BA: Risk of pneumonia in thermally injured patients requiring ventilatory support. J Burn Care Rehab 16:262-268, 1995.
  49. Offner PJ, Ogura H, Jordan BS, Pruitt BA, Cioffi WG: Effects of inhaled nitric oxide on right ventricular function in endotoxin shock. J Trauma 39:179-185, 1995.
  50. Barillo DJ, Cioffi WG, McManus WF, Pruitt BA: Thermal trauma resulting from motor vehicle operation or maintenance. Accident Analysis and Prevention 27:829-833, 1995.
  51. Pruitt BA, Cioffi WG: Diagnosis and treatment of smoke inhalation. J Int Care Med 10:115-125, 1995.
  52. Barillo DJ, McManus AT, Cioffi WG, McManus WF, Kim SH, Pruitt BA: Aeromonas bacteremia in burn patients. Burns 22:48-52, 1996.
  53. Davis KA, Brody JM, Cioffi WG: Computer tomography in blunt hepatic trauma. Arch Surg 31:255-260, 1996.
  54. Harvey KD, Barillo DJ, Hobbs CL, Mozingo DW, Fitzpatrick JC, Cioffi WG, McManus WF, Pruitt BA: Computer-assisted evaluation of hand and arm function following thermal injury. J Burn Care Rehab 17:176-180, 1996.
  55. Cioffi WG. The efficacy of inhaled nitric oxide in ARDS. Trauma Quarterly 12;237-255, 1996.
  56. Kelemen JJ, Cioffi WG, Mason AD, Mozingo DW, McManus WF, Pruitt BA: Effect of ambient temperature on metabolic rate after thermal injury. Ann Surg 223:406-412, 1996.
  57. Offner PJ, Ogura H, Jordan BS, Pruitt BA, Cioffi WG: Cardiopulmonary effects of combined nitric oxide inhibition and inhaled nitric oxide in porcine endotoxic shock. J Trauma 41:641-646, 1996.
  58. Walsh DS, Thavichaigarn P, Dheeradhada C, Jiarakul N, Pearce FC, Wiesmann WP, Cioffi WG, Webster HK: Prolonged alteration in gut permeability following nonthermal injury. Injury 27:491-4, 1996.
  59. Fitzpatrick JC, Cioffi WG: Ventilatory support following burns and smoke inhalation injury. Respiratory Care Clinics of North America. 3:21-49, 1997.
  60. Xu Y, Wichmann MW, Ayala A, Cioffi WG, Chaudry IH: Trauma-hemorrhage induces increased thymic apoptosis while decreasing IL-3 release and increasing GM-CSF. J Surg Res 68:24-30, 1997.
  61. Fitzpatrick JC, Jordan BS, Salman N, Williams J, Cioffi WG, Pruitt BA: The use of perfluorocarbon-associated gas exchange to improve ventilation and decrease mortality after inhalation injury in a neonatal swine model. J Pediatric Surg 32:192-6, 1997.
  62. Barillo DJ, Dickerson EE, Cioffi WG, Mozingo DW, Pruitt BA: Pressure-controlled ventilation for the long-range aeromedical transport of patients with burns. J Burn Care Rehab 18:200-205, 1997.
  63. Xu YX, Ayala A, Monfils B, Cioffi WG, Chaudry IH: Mechanism of intestinal mucosa I immune dysfunction following trauma-hemorrhage: Increased apoptosis associated with elevated Fas expression in Peyer’s Patches. J Surg Res 70:55-60, 1997.
  64. Wichmann MW, Angele MK, Ayala A, Cioffi WG, Chaudry IH: Flutamide: A novel agent for restoring the depressed cell-mediated immunity following soft-tissue trauma and hemorrhagic shock. Shock 8:242-248, 1997.
  65. Tasaki O, Goodwin CW, Saitoh D, Mozingo DW, Ishihara S, Brinkley WW, Cioffi WG, Pruitt BA: Effects of burns on inhalation injury. J Trauma 43:603-607, 1997.
  66. Angele MK, Wichmann MW, Ayala A, Cioffi WG, Chaudry IH: Testosterone receptor blockade after hemorrhage in males: Restoration of the depressed immune functions and improved survival following subsequent sepsis. Arch Surg 132:1201-14, 1997.
  67. Barillo DJ, Harvey KD, Hobbs CL, Mozingo DW, Cioffi WG, Pruitt BA: Prospective outcome analysis of a protocol for the surgical and rehabilitative management of burns to the hands. Plast Reconstr Surg 100:1442-51, 1997.
  68. Remmers DE, Wang P, Cioffi WG, Bland KI, Chaudry IH: Testosterone receptor blockade after trauma-hemorrhage improves cardiac and hepatic functions in males. Am J Physio/ 273: H2919-2925, 1997.
  69. Smail N, Wang P, Cioffi WG, Bland KI, Chaudry IH: What constitutes better resuscitation following trauma and hemorrhage: Rapid or slower rate of fluid administration? Surg Forum 8:125-127,1997.
  70. Wang P, Ba ZF, Cioffi WG, Chaudry IH: Factors responsible for producing the transition from the hyperdynamic to hypodynamic stage of sepsis: Role of a novel vasodilatory peptide, Adrenomedullin. Surg Forum 48:122-124, 1997.
  71. Angele MK, Xu YX, Ayala A, Catania RA, Cioffi WG, Bland KI, Chaudry IH: Gender differences in immune responses: Increased thymocyte apoptosis occurs only in males but not in females after hemorrhage. Surg Forum 48:95-97, 1997.
  72. Angele MK, Ayala A, Monfils BA, Cioffi WG, Bland KI, Chaudry IH: Testosterone and/or low estradiol: Normally required but harmful immunologically for males after trauma-hemorrhage. J Trauma 44:78-85, 1998.
  73. Remmers DE, Wang P, Cioffi WG, Bland KI, Chaudry IH: Chronic resuscitation after traumahemorrhage and acute fluid resuscitation improves hepatocellular function and cardiac output. Ann Surg 227:112-119, 1998.
  74. Smail N, Wang P, Cioffi WG, Bland KI, Chaudry IH: Resuscitation following uncontrolled venous hemorrhage: Does increased resuscitation volume improve regional perfusion? J Trauma 44:701-708, 1998.
  75. Wang P, Ba ZF, Cioffi WG, Bland KI, Chaudry IH: Is gut the “motor” for producing hepatocellular dysfunction after trauma and hemorrhagic shock? J Surg Res 74:141-148, 1998.
  76. Remmers DE, Bland KI, Cioffi WG, Wang P, Angele MK, Chaudry IH: Testosterone: The crucial hormone responsible for depressing myocardial function in males after trauma-hemorrhage. Ann Surg 227:790-799, 1998.
  77. Smail N, Catania RA, Wang P, Cioffi WG, Bland KI, Chaudry IH: Gut and liver: The organs responsible for increased nitric oxide production after trauma-hemorrhage and resuscitation. Arch Surg 133:399-405, 1998.
  78. Tasaki O, Mozingo DW, Ishihara S, Brinkley WW, Johnson AA, Smith RH, Srivastava O, Mason AD, Pruitt BA, Cioffi WG: Effect of Sulfo Lewis C on smoke inhalation injury in an ovine model. Crit Care Med 26:1238-1243, 1998.
  79. Angele MK, Smail N, Wang P, Cioffi WG, Bland KI, Chaudry IH: L-arginine restores the depressed cardiac output and regional perfusion after trauma-hemorrhage. Surgery 124:394-401, 1998.
  80. Wang P, Zhou M, Ba ZF, Cioffi WG, Chaudry IH: Upregulation of a novel potent vasodilatory peptide, adrenomedullin, during polymicrobial sepsis. Shock 10:118-122, 1998.
  81. Angele MK, Ayala A, Cioffi WG, Bland KI, Chaudry IH: Testosterone: The culprit for producing splenocyte immune depression following trauma-hemorrhage. Am J Physiol 274:C1530-C1536, 1998.
  82. Cioffi WG: Empiric treatment of potential fungal infections should be routine. Surgical Infections Forum 2:2-6, 1998.
  83. Angele MK, Knoferl MW, Ayala A, Cioffi WG, Bland KI, Chaudry IH: Male and female sex steroids: Do they produce deleterious or beneficial effects on immune responses following trauma-hemorrhage? Surg Forum 49:43-45, 1998.
  84. Catania RA, Angele MK, Ayala A, Cioffi WG, Bland KI, Chaudry IH: Dehydroepiandrosterone (DHEA): A novel steroid hormone therapy for restoring T-lymphocyte function following trauma and hemorrhage. Surg Forum 49:27-29, 1998.
  85. Safran H, Cioffi WG, Iannitti D, Mega A, Akerman P: Paclitaxel and concurrent radiation for locally advanced pancreatic carcinoma. Frontiers in Bioscience 3, e204-206, November 1, 1998.
  86. Mizushima Y, Wang P, Cioffi WG, Bland KI, Chaudry IH: Should body temperature be maintained at normothermia or hypothermia during resuscitation following trauma and hemorrhage? Surg Forum 49:45-48, 1998.
  87. Wang P, Ba ZF, Cioffi WG, Bland KI, Chaudry IH: Hepatocellular dysfunction after severe hypotension in the absence of blood loss is associated with increased IL-6 and PGE2. J Surg Res 80:136-142, 1998.
  88. Knoferl MW, Angele MK, Ayala A, Cioffi WG, Bland KI, Chaudry IH: Do different rates of fluid resuscitation adversely or beneficially influence immune responses following trauma-hemorrhage? J Trauma 46:23-33, 1999.
  89. Angele MK, Smail N, Ayala A, Cioffi WG, Bland KI, Chaudry IH: L-arginine: A unique amino acid for restoring the depressed immune functions following trauma-hemorrhage. J Trauma 46:34-41, 1999.
  90. Ghorra S, Reinert SE, Cioffi WG, Buczko G, Simms HH: Analysis of the effect of conversion from open to closed surgical intensive care unit. Ann Surg 229:163-171, 1999.
  91. Wang P, Ba ZF, Cioffi WG, Bland KI, Chaudry IH: The pivotal role of adrenomedullin in producing hyperdynamic circulation during the early stages of sepsis. Arch Surg 133:1298-1304, 1999.
  92. Angele MK, Catania RA, Ayala A, Cioffi WG, Bland KI, Chaudry IH: Dehydroepiandrosterone (DHEA): An inexpensive steroid hormone that decreases the mortality due to sepsis following trauma-induced hemorrhage. Arch Surg 133:1281-1288, 1999.
  93. Angele MK, Smail N, Knoferl MW, Ayala A, Cioffi WG, Chaudry IH: L-arginine restores splenocyte functions after trauma-hemorrhage potentially by improving splenic blood flow. Am J Physiol 276:C145-C151, 1999.
  94. Samy TS, Schwacha MG, Chung C-S, Cioffi WG, Bland KI, Chaudry IH: Proteasome participates in the alteration of signal transduction in T and B lymphocytes following trauma-hemorrhage. Biochim Biophys Acta 1453:92-104, 1999.
  95. Angele, MK, Knoferl MW, Schwacha MG, Ayala A, Bland KI, Cioffi WG, Josephson SL, Chaudry IH: Hemorrhage decreases macrophage inflammatory protein 2 and interleukin-6 release: A possible mechanism for increased wound infection. Ann Surg 229: 651-661, 1999.
  96. Safran H, Akerman P, Cioffi WG, Gaissert H, Joseph P, King T, Hesketh PJ, Wanebo H: Paclitaxel and concurrent radiation therapy for locally advanced adenocarcinomas of the pancreas, stomach, and gastroesophageal junction. Sem Rad Onco/ 9(suppl 1):53-57, 1999.
  97. Wang P, Ba ZF, Jarrar D, Cioffi WG, Bland KI, Chaudry IH: Mechanism of adrenal insufficiency following trauma and severe hemorrhage: Role of hepatic 11f3-hydroxysteroid dehydrogenase. Arch Surg 134:394-401, 1999.
  98. Wang P, Ba ZF, Cioffi WG, Bland KI, Chaudry IH: Salutary effects of ATP-MgCh on the depressed vascular endothelial cell function during hyperdynamic sepsis. Critical Care Med 27:959-964, 1999.
  99. Catania RA, Angele MK, Ayala A, Cioffi WG, Bland KI, Chaudry IH: Dehydroepiandrosterone (DHEA) restores immune function following trauma-hemorrhage by a direct effect on T-lymphocytes. Cytokine 11:443-450, 1999.
  100. Angele MK, Schwacha MG, Smail RA, Catania RA, Ayala A, Cioffi WG, Chaudry IH: Hypoxemia in the absence of blood loss upregulates inducible nitric oxide synthase expression and activity in macrophages. Am J Physiol 276:C285-C290, 1999.
  101. Catania RA, Schwacha MG, Cioffi WG, Bland KI, Chaudry IH: Does uninjured skin release proinflammatory cytokines following trauma and hemorrhage? Arch Surg 134:368-374, 1999.
  102. Tasaki O, Goodwin C, Mozingo DW, Cioffi WG, Ishihara S, Brinkley WW, Dubick MA, Smith RA, Srivastava O, Pruitt BA: Selectin blockade worsened lipopolysaccharide-induced lung injury in a swine model. J Trauma 46:1089-1095, 1999.
  103. Wang P, Yoo P, Zhou M, Cioffi WG, Ba ZF, Chaudry I H: Reduction in vascular responsiveness to adrenomedullin during sepsis. J Surg Res 85:59-65, 1999.
  104. Angele MK, Knoferl MW, Ayala A, Albina JE, Cioffi WG, Bland KI, Chaudry IH: Trauma-hemorrhage delays wound healing potentially by increasing proinflammatory cytokines at the wound site. Surgery 126:279-285, 1999.
  105. Cioffi WG: Society of University Surgeons Presidential address: SUS mentorship in Y2K – Passion, leadership, perspective. Surgery 126:101-111, 1999.
  106. Angele M, Knoferl MW, Schwacha MG, Ayala A, Cioffi WG, Bland KI, Chaudry IH: Sex steroids regulate pro- and anti-inflammatory cytokine release by macrophages after trauma-hemorrhage. Am J Physiol 277:C35-42, 1999.
  107. Schwacha MG, Ayala A, Cioffi WG, Bland KI, Chaudry IH: Role of protein kinase C in cyclic AMP mediated suppression of T-lymphocyte activation following burn injury. Biochim Biophys Acta 1455:45-53, 1999.
  108. Koo DJ, Zhou M, Jackman D, Cioffi WG, Bland KI, Chaudry IH, Wang P: Is gut the major source of proinflammatory cytokine release during polymicrobial sepsis? Biochim Biophys Acta 1454:289-295, 1999.
  109. Yang S, Cioffi WG, Bland KI, Chaudry IH, Wang P: Differential alterations in systemic and regional oxygen delivery and consumption during the early and late stages of sepsis. J Trauma 47:706-712, 1999.
  110. Angele MK, Xu YX, Ayala A, Schwacha MG, Catania RK, Cioffi WG, Bland KI, Chaudry IH: Gender dimorphism in trauma-hemorrhage induced thymocyte apoptosis. Shock 12:316-322, 1999.
  111. Angele MK, Knoferl M, Song GY, Schwacha MG, Ayala A, Cioffi WG, Bland KI, Chaudry IH: Gender dimorphism in the immune response following trauma hemorrhage: Involvement of p38 MAP kinase signal transduction pathways. Surg Forum 50:278-280, 1999.
  112. Knoferl M, Angele MK, Diodato MD, Ayala A, Cioffi WG, Bland KI, Chaudry IH: Surgical ovariectomy produces immunosuppression following trauma-hemorrhage and increases mortality from subsequent sepsis. Surg Forum 50:235-237, 1999.
  113. Wang P, Ba ZF, Cioffi WG, Bland KI, Chaudry IH: Does chronic resuscitation after trauma-hemorrhage and acute fluid replacement produce any salutary effects on cardiovascular function and inflammatory cytokine and inflammatory cytokine release? The FASEB J 13:A756, 1999.
  114. Mizushima Y, Wang P, Cioffi WG, Bland KI, Chaudry IH: Should normothermia be restored and maintained after trauma and hemorrhage? J Trauma 48:58-65, 2000.
  115. Mizushima Y, Wang P, Cioffi WG, Bland KI, Chaudry IH: Preinduction of heat shock proteins protects cardiac and hepatic functions following trauma and hemorrhage. Am J Physio/ 278: R352-R359, 2000.
  116. Angele MK, Knoferl M, Schwacha MG, Ayala A, Cioffi WG, Bland KI, Chaudry IH: Impairment of wound healing following hemorrhage is associated with decreased collagen deposition. Crit Care & Shock 3:49-56, 2000.
  117. Kahlke V. Angele MK, Ayala A, Schwacha MG, Cioffi WG, Bland KI, Chaudry IH: Immune dysfunction following trauma-hemorrhage: Influence of gender and age. Cytokine 12:69-77, 2000.
  118. Jarrar D, Wang P, Song GY, Knoferl MW, Cioffi WG, Bland KI, Chaudry IH: Metoclopramide: A novel adjunct for improving cardiac and hepatocellular functions following trauma-hemorrhage and resuscitation. Am J Physiol 278:E90-E96, 2000.
  119. Mizushima Y, Wang P, Cioffi WG, Bland KI, Chaudry IH: Restoration of body temperature to normothermia during resuscitation following trauma-hemorrhage improves the depressed cardiovascular and hepatocellular functions. Arch Surg 135:175-181, 2000.
  120. Mizushima Y, Wang P, Cioffi WG, Bland KI, Chaudry IH: Should body temperature be maintained at normothermia during resuscitation following trauma and hemorrhage? J Trauma 48:58-65, 2000.
  121. Safran H, Wanebo HJ, Hesketh PJ, Akerman P, Iannitti D, Cioffi WG, DiPetrillo T, Wolf B, Koness J, McAnaw R, Moore T, Chen M, Keane KR: Paclitaxel and concurrent radiation for gastric cancer. Int J Radiation Oncology Biol Phys 46:889-894, 2000.
  122. Wang P, Zhou M, Cioffi WG, Bland KI, Ba ZF, Chaudry IH: Is prostacyclin responsible for producing the hyperdynamic response during early sepsis? Critical Care Medicine 28:1534-1539, 2000.
  123. Koo DJ, Yoo P, Cioffi WG, Bland KI, Chaudry IH, Wang P: Mechanism of the beneficial effects of pentoxifylline during sepsis: Maintenance of adrenomedullin responsiveness and downregulation of proinflammatory cytokines. J Surg Res 91:70-76, 2000.
  124. Knoferl MW, Angele MK, Ayala A, Cioffi WG, Bland KI, Chaudry IH: Insight into the mechanism by which Metoclopramide improves immune functions after trauma-hemorrhage. Amer J Physiol Ce/1 Physiol 279:C72-80, 2000.
  125. Jarrar D. Wang P, Song GY, Cioffi WG, Bland KI, Chaudry IH: Inhibition of tyrosine kinase signaling following trauma-hemorrhage: A novel approach to improving organ function and decreasing susceptibility to subsequent sepsis. Ann Surg 231:399-407, 2000.
  126. Jarrar D, Wang P, Cioffi WG, Bland KI, Chaudry IH: Mechanisms of the salutary effects of dehydroepiandrosterone after trauma-hemorrhage: Direct or indirect effects on cardiac and hepatocellular functions? Arch Surg 135:416-22, 2000.
  127. Knoferl MW, Diodato MD, Angele MK, Ayala A, Cioffi WG, Bland KI, Chaudry IH: Do female sex steroids adversely or beneficially affect the depressed immune responses in males following trauma-hemorrhage? Arch Surg 135:425-33, 2000.
  128. Ba ZF, Wang P, Koo DJ, Cioffi WG, Bland KI, Chaudry IH: Alterations in tissue oxygen consumption and extraction following trauma and hemorrhagic shock. Crit Care Med 28:2837-2842, 2000.
  129. Brody JM, Leighton DB, Murphy B L, Abbott GF, Vaccaro JP, Jagminas L, Cioffi WG: CT of blunt trauma bowel and mesenteric injury: Typical findings and pitfalls in diagnosis. Radiographics 20:1525-1536, 2000.
  130. Jarrar D, Wang P, Cioffi WG, Bland KI, Chaudry IH: The critical role of oxygen radicals in the initiation of hepatic depression after trauma hemorrhage. J Trauma 49(5):879-85, 2000.
  131. Mizushima V, Wang P, Jarrar D, Cioffi WG, Bland KI, Chaudry IH: Estradiol administration following trauma-hemorrhage improves cardiovascular and hepatocellular functions in males. Ann Surg 232(5):673-9, 2000.
  132. Jarrar D, Wang P, Knoferl M, Ba ZF, Cioffi WG, Bland KI, Chaudry IH: Does early infusion of red blood cells following trauma and hemorrhage improve organ functions? Crit Care Med 28(10):3498-504, 2000.
  133. Ba ZF, Wang P, Koo DJ, Cioffi WG, Bland KI, Chaudry IH: Testosterone receptor blockade attenuates adrenal insufficiency after trauma-hemorrhage. Am J Physiol 279(5):R1841-8, 2000.
  134. Samy TSA, Schwacha MG, Cioffi WG, Bland KI, Chaudry IH: Androgen and estrogen receptors in T lymphocytes: The effects of flutamide and trauma-hemorrhage. Shock 14(4):465-70, 2000.
  135. Jarrar D, Wang P, Cioffi WG, Bland KI, Chaudry IH: The female reproductive cycle is an important variable in the response to trauma-hemorrhage and resuscitation. Am J Physio/ 279(3): H1015-21, 2000.
  136. Jarrar D, Wang P, Knoferl M, Kuebler J, Cioffi WG, Bland KI, Chaudry IH: Insight into the mechanism by which estradiol improves organ functions following trauma-hemorrhage. Surgery 128(2):2837-42, 2000.
  137. Kahlke V, Angele MK, Schwacha MG, Ayala A, Cioffi WG, Bland KI, Chaudry IH: Reversal of sexual dimorphism in splenic T-lymphocyte responses following trauma-hemorrhage with aging. Am J Physio/ 278(3):C509-16, 2000.
  138. Knoferl MW, Jarrar D, Schwacha MG, Angele MK, Cioffi WG, Bland KI, Chaudry IH: Severe hypothermia in the absence of blood loss causes a gender dimorphic immune response. Am J Physio/ – Cell Physio/ 279(6):C2004-10, 2000.
  139. Schneider CP, Nickel EA, Samy TS, Schwacha MG, Cioffi WG, Bland KI, Chaudry IH: The aromatase inhibitor, 4-hydroxyandrostenedione, restores immune responses following trauma-hemorrhage in males and decreases mortality from subsequent sepsis. Shock 14(3):347-53, 2000.
  140. Wang P, BA ZF, Koo DJ, Cioffi WG, Bland KI, Chaudry IH: Continuous resuscitation after hemorrhage and acute fluid replacement improves cardiovascular responses. Surgery 129(5):559-66, 2001.
  141. Rocco Jr TR, Reinert SE, Cioffi WG, Harrington DT, Buczko G, Simms HH: A 9-year, single-institution, retrospective review of death rate and prognosis factors in adult respiratory distress syndrome. Ann Surg 233(3):414-422, 2001.
  142. Saitoh D, Shirani KZ, Cioffi WG, Kizaki T, Ohmo H, Okada V, Mason AD Jr, Pruitt BA Jr: Changes in the tissue and plasma superoxide dismutase (SOD) levels in a burned rat model. Tohoku J Experimental Med 193(1):27-36, 2001.
  143. Safran H, Moore T, Iannitti D, DePetrillo T, Akerman P, Cioffi W, Harrington D, Quirk D, Rathore R, Cruff D, Vakharia J, Vora S, Savarese D, Wanebo H: Paclitaxel and concurrent radiation for locally advanced pancreatic cancer. Int J Radiation Oncology Biol Phys 49{5):1275-1279, 2001.
  144. Song GY, Chung CS, Cioffi WG, Ayala A. Septic immune dysfunction: Is there a role for NO-mediated alterations in p38 MAPK activation? Surg Forum 48:69-171, 2001.
  145. Cioffi WG: What’s new in burns and metabolism [review]. J Am Co/1 Surg 192(2):241-254, 2001.
  146. Knoferl MW, Diodato MD, Schwacha MG, Cioffi WG, Bland KI, Chaudry IH: Cyclooxygenase-2-mediated regulation of Kupffer cell interleukin-6 production following trauma-hemorrhage and subsequent sepsis. Shock 16(6):479-83, 2001.
  147. Knoferl MW, Angele MK, Diodato MD, Schwacha MG, Ayala A, Cioffi WG, Bland KI, Chaudry IH: Female sex hormones regulate macrophage function after trauma-hemorrhage and prevent increased death rate of subsequent sepsis. Ann Surg 235(1):105-12, 2002.
  148. Song GV, Chung CS, Jarrar D, Cioffi WG, Ayala A: Mechanism of immune dysfunction in sepsis: Inducible nitric-oxide mediated alterations in p38 MAPK activation. J Trauma 53(2):276-83, 2002.
  149. Safran H, Dipetrillo T, Iannitti D, Quirk D, Akerman P, Cruff D, Cioffi W, Shah S, Ramdin N, Rich T: Gemcitabine, paclitaxel, and radiation for locally advanced pancreatic cancer: A Phase I trial. International Journal of Radiation Oncology, Biology, Physics. 54(1):137-41, 2002 Sep 1.
  150. Song GV. Chung CS. Jarrar D. Cioffi WG. Ayala A. Mechanism of immune dysfunction in sepsis: inducible nitric oxide-mediated alterations in p38 MAPK activation. Journal of Trauma-Injury Infection & Critical Care. 53(2):276-82; discussion 282-3, 2002 Aug.
  151. Ayala A. Chung CS. Lomas J L. Song GV. Doughty LA. Gregory SH. Cioffi WG. LeBlanc BW. Reichner J. Simms HH. Grutkoski PS. Shock-induced neutrophil-mediated priming for acute lung injury in mice: divergent effects of TLR-4 and TLR-4/FasL deficiency. American Journal of Pathology. 161(6):2283-94, 2002 Dec.
  152. Biffl W L. Harrington DT. Cioffi WG. Implementation of a tertiary trauma survey decreases missed injuries. Journal of Trauma-Injury Infection & Critical Care. 54(1):38-43; discussion 43-4, 2003 Jan.
  153. Lomas JL. Chung CS. Grutkoski PS. LeBlanc BW. Lavigne L. Reichner J. Gregory SH. Doughty LA. Cioffi WG. Ayala A. Differential effects of macrophage inflammatory chemokine-2 and keratinocyte-derived chemokine on hemorrhage-induced neutrophil priming for lung inflammation: assessment by adoptive cell transfer in mice. Shock. 19(4):358-65, 2003 April.
  154. Biffl WL. Cioffi WG. Medical disasters: are we really prepared? An analysis of the station fire. Medicine & Health, Rhode Island. 86(11):342-3, 2003 Nov.
  155. Gutman D. Biffl WL. Suner S. Cioffi WG. The station nightclub fire and disaster preparedness in Rhode Island. Medicine & Health, Rhode Island. 86(11):344-6, 2003 Nov.
  156. Mahoney EJ. Biffl WL. Harrington DT. Cioffi WG. Isolated brain injury as a cause of hypotension in the blunt trauma patient. Journal of Trauma-Injury Infection & Critical Care. 55(6):1065-9, 2003 Dec.
  157. Rhee RJ. Carlton S. Lomas JL. Lane C. Brossay L. Cioffi WG. Ayala A. Inhibition of CD1d activation suppresses septic mortality: a role for NK-T cells in septic immune dysfunction. Journal of Surgical Research. 115(1) :74-81, 2003 Nov.
  158. Iannitti DA. Gregg SC. Mayo-Smith WW. Tomolonis RJ. Cioffi WG. Pricolo VE. Portal venous gas detected by computed tomography: is surgery imperative? Digestive Surgery. 20(4):306-15, 2003.
  159. Biffl WL. Schiffman JD. Harrington DT. Sullivan J. Tracy TF Jr. Cioffi WG. Legal prosecution of alcohol-impaired drivers admitted to a Level I trauma center in Rhode Island. Journal of Trauma Injury Infection & Critical Care. 56(1) :24-9, 2004 Jan.
  160. Majercik S, Biffl WL, Cioffi WG, Harrington DT. Trauma triage criteria: Does mechanism matter? Journal of Trauma, 56:229, 2004 Feb.
  161. Mahoney EJ, Harrington DT, Biffl WL, Oka T, Cioffi WG. Lessons learned from a nightclub fire: Part I -Institutional disaster preparedness. Journal of Trauma, 56:462, 2004 Feb.
  162. Grutkoski PS, Chen Y, Chung CS, Cioffi WG, Ayala A. Putative mechanism of hemorrhage-induced leukocyte hyporesponsiveness; induction of suppressor of cytokine signaling-3. Journal of Trauma. 56(4):742-7; discussion 747-8, 2004 Apr.
  163. Cioffi WG, Coburn N. Complex issue of surgical outcome and hospital volume for several high-risk procedures. Medicine and Health Rhode Island 87(6):192-3, 2004 June.
  164. Safran H, DiPetrillo T, Nadeem A, Steinhoff M, Tantravahi U, Rathore H, Rathore R, Wanebo H, Hughes M, Maia C, Tsai JY, Pasquariello T, Pepper JR, Cioffi WG, et. al. Trastuzumab, paclitaxel, cisplatin, and radiation for adenocarcinoma of the esophagus: a phase I study. Cancer Investigations 22(5) :670-7, 2004.
  165. Tsikitis V, Biffl WL, Majercik S, Harrington DT, Cioffi WG. Selective clinical management of anterior abdominal stab wounds. American Journal of Surgery 188(6):807-12, 2004 Dec.
  166. Harrington DT, Biffl WL, Cioffi WG. The station nightclub fire. Journal of Burn Care Rehabilitation 26(2):141-3, March 2005.
  167. Mahoney EJ, Harrington DT, Biffl WL, Metzger J, Oka T, Cioffi WG. Lessons learned from a nightclub fire: institutional disaster preparedness. Journal of Trauma 58(3):487-91, March 2005.
  168. Harrington DT, Connolly M, Biffl WL, Majercik SD, Cioffi WG. Transfer times to definitive care facilities are too long: A consequence of an immature trauma system. Annals of Surgery 2005 June; 241:961-968; discussion 966-8.
  169. Biffl WL, Harrington DT, Majercik SD, Starring J, Cioffi WG. The evolution of trauma care at a level I trauma center. Journal of the American College of Surgeons 2005 June; 200:922-929.
  170. Majercik S, Tashjian RZ, Biffl WL, Harrington DT, Cioffi WG. Halo vest immobilization in the elderly: A death sentence? Journal of Trauma 2005 Aug; 59(2):350-356; discussion 356-358.
  171. Lomas-Neira J, Chung CS, Grutkoski PS, Dunican A, Simms HH, Cioffi WG. Divergent roles of murine neutrophil chemokines in hemorrhage induced priming for acute lung injury. Cytokine 2005 Aug 7: 31(3):169-79.
  172. Song GY, Chung CS, Rhee RJ, Cioffi WG, Ayala A. Loss of signal transducer and activator of transduction 4 or 6 signaling contributes to immune cell morbidity and mortality in sepsis. Intensive Care Medicine 2005 Nov; 31(11):1564-1569.E pub 2005 Sept 20.
  173. Perl M, Chung CS, Lomas-Niera J, Rachel TM, Biffl WL, Cioffi WG, Ayala A. Silencing of Fas, but not caspase-8, in lung epithelial cells ameliorates pulmonary apoptosis, inflammation, and neutrophil influx after hemorrhagic shock and sepsis. Am J Pathol 2005 Dec;167(6):1545-1559.
  174. Iannitti DI, Dipetrillo T, Akerman P, Barnett JM, Maia-Acuna C, Cruff D, Miner TJ, Martel D, Cioffi WG, Remis M, Kennedy T, Safran H. Erlotinib and chemoradiation followed by maintenance erlotinib for locally advanced pancreatic cancer: a phase I study. Amer J Clin Oncol 2005; 28(6):570-575.
  175. Tashjian RZ, Majercik S, Biffl WL, Palumbo MA, Cioffi WG. Halo-vest immobilization increases early morbidity and mortality in elderly odontoid fractures. Journal of Trauma 2006 Jan; 60(1):199-203.
  176. Biffl WL, Egglin T, Benedetto B, Gibbs F, Cioffi WG. Sixteen-slice CT-angiography is a reliable noninvasive test that allows liberal screening for blunt cerebrovascular injuries. The Journal of Trauma 2006 April; 60(4):745-51: discussion 751-2.
  177. Brunetti-Pierri N, Ng T, Iannitti DA, Palmer DJ, Beaudet AL, Finegold MJ, Carey KD, Cioffi WG. Improved hepatic transduction, reduced systemic vector dissemination, and long-term transgene expression by delivering helper-dependent adenoviral vectors into the surgically isolated liver of nonhuman primates. Human Gene Therapy 2006 Apr; 17:391-404.
  178. Napolitano LM, Cioffi WG, Lewis FR Jr. Surgical Critical Care. Journal of Trauma 2006 Apr; 60(4):923.
  179. Chung CS, Watkins L, Funches A, Lomas-Neira J, Cioffi WG, Ayala A. Deficiency of {gamma} {delta} T-lymphocytes contributes to mortality and immunosuppression in sepsis. American Journal of Physiology 2006 Nov; 291(5);R1338-43. Epub 2006 Jun 22.
  180. Smith HE, Biffl WL, Majercik SD, Jednacz J, Lambiase R, Cioffi WG. Splenic artery embolization: Have we gone too far? J Trauma 2006 Sep; 61(3):541-4; discussion 546-6.
  181. Iannitti DA, Coburn NG, Samberg J, Ryder BA, Monchik J, Cioffi W G . Use of the round ligament of the liver to decrease pancreatic fistulas: a novel technique. J Am Coll Surg 2006 Dec; 203(6):857-Epub 2006 Oct 25.
  182. Perl M, Chung CS, Perl U, Biffl WL, Cioffi WG, Ayala A. Beneficial versus detrimental effects of neutrophils are determined by the nature of the insult. J Am Coll Surg 2007 May; 204(5):840-52: discussion 852-3.
  183. Perl M, Chung CS, Perl U, Lomas-Neira J, de Paepe M, Cioffi WG, Ayala A, Fas-induced pulmonary apoptosis and inflammation during indirect acute lung injury. Am J Respir Crit Care Med 2007 Sep 15; 176(6 ):591-601.
  184. Swan R, Chung CS, Albina J, Cioffi W, Perl M, Ayala A. Polymicrobial sepsis enhances clearance of apoptotic immune cells by splenic macrophages. Surgery 2007 Aug; 142(2):253-61.
  185. Abodeely A, Roye GD, Harrington DT, Cioffi WG. Pregnancy outcomes after bariatric surgery: maternal, fetal, and infant implications. Surg Obes Re/at Dis 2008 May-Jun;4(3) :464-71. Epub 2007 Nov 5.
  186. Harrington DT, Roye GD, Ryder BA, Miner TJ, Richardson P, Cioffi WG. A time-cost analysis of teaching a laparoscopic entero-enterostomy. J Surg Educ 2007 Nov-Dec;64(6) : 342-5.
  187. Mahoney EJ, Biffl WL, Cioffi WG. Mass-casualty incidents: How does an ICU prepare? J Intensive Care Med 2008 May 25.
  188. Klaristenfeld DD, Chupp M, Cioffi WG, White RE. An international volunteer program for general surgery residents at Brown Medical School: the Tenwek Hospital Africa Experience. J Am Coll Surg 2008 Jul;207(1): 125-8. E Pub 2008 Apr 24.
  189. Ng T, Ryder BA, Machan JT, Cioffi WG. Decreasing the incidence of prolonged air leak right upper lobectomy with the anterior fissureless technique. J Thoracic Cardiovascular Surg 2010 April:139(4): 1007-11. Epub 2009 Aug 15.
  190. Alam HB, Chipman JG, Luchette FA, Shapiro MJ, Spain DA, Cioffi W. Training and certification in surgical critical care: a position paper in the Surgical Critical Care Program Directors Society. J Trauma 2010 Aug;69(2):471-4.
  191. Heffernan DS, Thakkar RK, Monaghan SF, Ravindran R, Adams CA Jr, Kozloff MS, Gregg SC, Connolly MD, Machan JT, Cioffi WG. Normal presenting vital signs are unreliable in geriatric blunt trauma victims. J Trauma 2010 Oct:69(4) :813-20.
  192. Cairns CB, Maier RV, Adeoye 0, Baptise D, Barsan WG, Blackbourne L, Burd R, Carpenter C, Chang D, Cioffi W, et al. NIH Roundtable on Emergency Trauma Research. Ann Emerg Med, 2010 Nov:56(5):538-550.
  193. Thakkar, RK, Chung, CS, Chen, Y, Monaghan, SF, Lomas-Neira J, Heffernan, DS, Cioffi, WG, Ayala, A. Local Tissue Expression of the Cell Death Ligand, FasL, Plays a Central Role in the Development of Extra-Pulmonary Acute Lung Injury. Shock, 2011; 36(2), 138-143.
  194. Heffernan, DS, Vera, RM, Monaghan, SF, Thakkar, RK, Kozloff, MS, Connolly, MD, Gregg, SC, Harrington, DT, Adams, CA, Cioffi, WG. The Impact of Socio-Ethnic Factors on Outcomes Following Traumatic Brain Injury. Journal of Trauma, 2011; 70(3): 527-534.
  195. Monaghan, SF, Heffernan, DS, Thakkar, RK, Machan, JT, Reinert, SE, Connolly, MD, Gregg, SC, Kozloff, MS, Adams, CA, Cioffi, WG. The Development of a Urinary Tract Infection is Associated with Increased Mortality in Trauma Patients. Journal of Trauma, 2011; 71(6): 1569-74.
  196. Miner TJ, Cohen J, Charpentier K, McPhillips J, Marvell L, Cioffi WG. The palliative triangle: improved patient selection and outcomes associated with palliative operations. Arch Surg. 2011 May;146(5) :517-22.
  197. Monaghan, SF, Thakkar, RK, Heffernan DS, Huang, X, Chung, CS, Lomas-Neira, J, Cioffi, WG, Ayala, A. Mechanisms of Indirect Acute Lung Injury: A Novel Role for the Co-Inhibitory Receptor, Programmed Death-1 (PD-1). Annals of Surgery, 2012; 255(1):158-164.
  198. Heffernan, DS, Monaghan SF, Thakkar RK, Machan JT, Cioffi WG, Ayala A. Failure to normalize lymphopenia following trauma is associated with increased mortality, independent of the leukocytosis pattern. Crit Care, 2012 Jan 20:16(1)R12.
  199. Ng T, Ryder BA, Chern H, Sellke FW, Machan JT, Harrington DT, Cioffi WG. Leukocyte-depleted blood transfusion is associated with decreased survival in resected early-stage lung cancer. J Thoracic Cardiovasc Surg. 2012 Apr;143:4):815-9.
  200. Dossett LA, Fox EE, del Junco DJ, Zaydfudim V, Kauffmann R, Shelton J, Wang W, Cioffi WG, Holcomb JB, Cotton BA. Don’t forget the poster! Quality and content variables associated with accepted abstracts at a national meeting. J Trauma Acute Care Surg. 2012 May;72(5):1429-34.
  201. Thakkar RK, Monaghan SF, Adams CA Jr, Stephen A, Connolly MD, Gregg S, Cioffi WG, Heffernan DS. Empiric antibiotics pending bronchoalveolar lavage data in patients without pneumonia significantly alters the flora, but not the resistance profile, if a subsequent pneumonia develops. J Surg Res. 2012 Jul 26. Epub 2012 Jul 26.
  202. Monaghan SF, Blakely AM, Richardson PJ, Miner TJ, Cioffi WG, Harrington DT. The reflective statement: a new tool to assess resident learning. J Surg Res. 2012 Aug 3. Epub 2012 Aug 3.
  203. Monaghan SF, Thakkar RK, Tran ML, Huang X, Cioffi WG, Ayala A, Heffernan DS. Programmed death 1 expression as a marker for immune and physiological dysfunction in the critically ill surgical patient. Shock. 2012 Aug;38(2):117-22.
  204. Herron, T, Monaghan, S, Gravenstein, S, Cioffi, W, Ayala, A, Heffernan, D. The association between inflammatory and hemodynamic response in geriatric trauma patients. Surg. Infect. 2012. 13:S35.
  205. Fox, ED, Monaghan, SF, Chamberlain, CJ, Machan, JT, Cioffi, WG, Gravenstein, S, Ayala, A, Heffernan, DS. Early neutrophilia is predictive of higher mortality in moderate to severely injured geriatric trauma patients. Shock. 2012 37(6) (Suppl 1):46.
  206. Heffernan, DS, Monaghan, SF, Fox, ED, Kettenmann M, Machan, JT, Gravenstein, S, Cioffi, WG, Ayala, A, Geriatric patients are extremely vulnerable to trauma-induced lymphopenia. Shock. 2012 37(6) (Suppl 1):48.
  207. Duron VP, Monaghan SF, Connolly MD, Gregg SC, Stephen AH, Adams CA Jr, Cioffi WG, Heffernan DS. Undiagnosed medical comorbidities in the uninsured: a predictor of mortality following trauma. J Trauma Acute Care Surg. 2012 Nov; 73(5):1093-8; discussion 1098-9.
  208. Monaghan SF, Adams CA Jr, Stephen AH, Connolly MD, Gregg SC, Machan JT, Cioffi WG, Heffernan DS. Infections after trauma are associated with subsequent cardiac injury. J Trauma Acute Care Surg. 2012 Nov; 73(5):1079-84; discussion 1084-5.
  209. Cioffi WG. Governors’ Committee to Study the Fiscal Affairs of the College. Bull Am Coll Surg. 2013 Apr;98(4) :51-2.
  210. Thakkar RK, Monaghan SF, Adams CA Jr, Stephen A, Connolly MD, Gregg S, Cioffi WG, Heffernan DS. Empiric antibiotics bronchoalveolar lavage in patients without pneumonia significantly alters the flora, but not the resistance profile, if a subsequent pneumonia develops. J Surg Res. 2013 May;181(2) :323-8. Epub 2012 Jul 26.
  211. Drolet BC, Sangisetty S, Tracy TF, Cioffi WG. Surgical residents’ perceptions of 2011 Accreditation Council for Graduate Medical Education duty hour restrictions. JAMA Surg. 2013 May;148(5):427-33.
  212. Heffernan DS, Monaghan SF, Thakkar RK, Tran ML, Chung CS, Gregory SH, Cioffi WG, Ayala A. Inflammatory mechanisms in sepsis: elevated invariant natural killer T-cell numbers in mouse and their modulary effect on macrophage. Shock. 2013 Aug;40(2):122-8.
  213. Brunetti-Pierri N, Ng T, Iannitti D, Cioffi W, Stapleton G, Law M, Breinholt J, Palmer D, Grove N, Rice K, Bauer C, Finegold M, Beaudet A, Mullins C, Ng P. Transgene expression up to 7 years in nonhuman primates following hepatic transaction with helper-dependent adenoviral vectors. Hum Gene Ther. 2013 Aug;24(8): 761-5.
  214. Drolet BC, Sangisetty S, Mulvaney PM, Ryder BA, Cioffi WG. A mentorship-based preclinical elective increases exposure, confidence, and interest in surgery. Am J Surg. 2014 Feb; 207(2):179-86. doi: 10.1016/j.amjsurg.2013.07.031. Epub 2013 Oct 2. PMID: 24269035
  215. Fox ED, Heffernan DS, Cioffi WG, Reichner JS. Neutrophils from critically ill septic patients mediate profound loss of endothelial barrier integrity. Crit Care. 2013 Oct 7;17(5): R226. PMID: 24099563
  216. Okhah Z, Morrissey P, Harrington DT, Cioffi WG, Charpentier KP. Assessment of surgical residents in a vascular anastomosis laboratory. J Surg Res. 2013 Nov;185(1):450-4. Epub 2013 Jun 6.
  217. Heffernan DS, Monaghan SF, Chung CS, Cioffi WG, Gravenstein S, Ayala A. Hum Immunol. A divergent response of innate regulatory T-cells to sepsis in humans: circulating invariant natural killer T-cells are preserved. 2014 Mar; 75(3):277-82. Epub 2013 Nov 20. PMID: 24269692
  218. Napolitano LM, Savarise M, Paramo JC, Soot LC, Todd SR, Gregory J, Timmerman GL, Cioffi WG, Davis E, Sachdeva AK. Are general surgery residents ready to practice? A survey of the American College of Surgeons Board of Governors and Young Fellows Association. J Am Coll Surg. 2014 May; 218(5):1063-1072.e31. Epub 2014 Feb 6. PMID: 24661851
  219. Cioffi WG, Harrington DT. A multi-institutional benchmark of burn outcomes as a spur to further improvements in burn care. Ann Surg. 2014 May; 259(5):842-3. PMID: 24717373
  220. Blakely AM, Heffernan DS, McPhillips J, Cioffi WG, Miner TJ. Elevated C-reactive protein as a predictor of patient outcomes following palliative surgery. J Surg Oncol. 2014 Nov;110(6):651-5. Epub 2014 June 25. PMID: 24964899
  221. Monti PM, Colby SM, Mastroleo NR, Barnett NP, Gwaltney CJ, Apodaca TR, Rohsenow DJ, Magil IM, Gogineni, A Mello MJ, Biffl WL, Cioffi WG. Individual versus significant-other enhanced brief motivational intervention for alcohol in emergency care. J Consult Clin Psychol. 2014 Dec;82(6) :936-48. Epub 2014 11. PMID: 25111430
  222. Ottinger ME, Monaghan SF, Gravenstein S, Cioffi WG, Ayala A, Heffernan DS. The geriatric cytokine response to trauma: time to consider a new threshold. Surg Infect (Larch mt) 2014 Dec;15(6) :800-5. PMID: 25494395
  223. Davis KA, Dente CJ, Burlew CC, Jurkovich GJ, Reilly PM, Toshlog EA, Cioffi WG. Refining the operative curriculum of the acute care surgery fellowship. J Trauma Acute Care Surg. 2015 Jan;78(1) :192-6. PMID: 25539221
  224. Young JS, Monaghan SF, Chung CS, Cioffi WG, Ayala A, Heffernan DS. Divergent invariant natural killer T-cell response to sepsis of abdominal vs. non-abdominal origin in human beings. Surg Infect (Larchmt). 2015 Feb;16(1) :29-35. PMID: 25761077
  225. Cioffi WG. Responsibility. J Trauma Acute Care Surg. 2015 Apr;78(661-70) PMID: 25742259
  226. Harrington DT, Miner TJ, Ng T, Charpentier KP, Richardson P, Cioffi WG. What shape is your resident in? Using a radar plot to guide a milestone clinical competency discussion. J Surg Educ. 201 5 Nov-Dec;72(6):e294-8. PMID: 26143521
  227. Vidri RJ, Blakely AM, Kulkarni SS, Vaghjiani RG, Heffernan DS, Harrington DT, Cioffi WG, Miner TJ. American College of Surgeons National Surgical Quality Improvement Program as a quality measurement tool for advanced cancer patients. Ann Palliat Med. 2015 Oct;4(4):200-6. PMID: 26541399
  228. Sawhney JS, Stephen AH, Nunez H, Luecke I SN, Kheirbek T, Adams CA Jr, Cioffi WG, Heffernan DS. Effect of PD-1: PD-L1 in Invariant Natural Killer T-Cell Emigration and Chemotaxis Following Sepsis. Shock 2016 May;45(5):534-9. PMID: 267 1 7 1 05
  229. Sawhney JS, Stephen AH, Nunez H, Lueckel SN, Kheirbek T, Adams CA, Cioffi WG, Heffernan DS. Impact of type of health insurance on infection rates among young trauma patients. Surg Infect 2016 Oct:17(5):541-6. PMID: 27244084
  230. Gregg SC, Heffernan DS, Connolly MD, Stephen AH, Leuckel SN, Harrington DT, Machan JT, Adams CA, Cioffi WG. Teaching leadership in trauma resuscitation: Immediate feedback from a real-time, competency-based evaluation tool shows long-term improvement in resident performance. J Trauma Acute Care Surg 2016 Oct:81(4) :729-34. PMID: 27488489.
  231. Jenkins DH, Cioffi WG, Cocanour CS, Davis KA, Fabian TC, Jurkovich GJ, Rozycki GS, Scalea TM, Stassen NA, Stewart RM; Coalition for National Trauma Research (CNTR). Position statement of the Coalition for National Trauma Research on the National Academies of Sciences, Engineering and Medicine report, a National Trauma Care System: Integrating Military and Civilian Trauma Systems to Achieve Zero Preventable Deaths After Injury. J Trauma Acute Care Surg 2016 Nov;81{5) :816-818. PMID: 27533908.
  232. Monaghan SF, Chung CS, Chen Y, Lomas-Neira J, Fairbrother WG, Heffernan DS, Cioffi WG, Ayala A. Soluble programmed cell death receptor-1 (sPD-1): A potential biomarker with anti-inflammatory properties in human and experimental acute care respiratory distress syndrome (ARDS). J Transl Med 2016 Nov 11:14(1):312.
  233. Young YA, Fallon EA, Heffernan DS, Efron PA, Cioffi WG, Ayala A. Improved survival after induction of sepsis by cecal slurry in PD-1 knockout murine neonates. Surgery 2016 Dec 21. (Epub ahead of print) PMID: 28012568.
  234. Davis KA, Fabian TC, Cioffi WG. The toll of death and disability from traumatic injury in the United States – The “Neglected Disease” of modern society, still neglected after 50 years. JAMA Surg 2017 Mar 1;152(3) :221-222. PMD: 28030708.
  235. Chun TT, Garcia-Toca M, Eng JF, Slaiby J, Marcaccio EJ Jr, Cioffi WG, Heffernan DS. Postoperative infections are associated with increased risk of cardiac events in vascular patients. Ann Vasc Surg 2017 Feb 23 (Epub ahead of print) PMID: 28238924.

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